The use of outdated software was not just a cosmetic flaw; it signaled a broader negligence in keeping up with technological advancements. Stay informed about the latest darknet marketplaces, secure browsing practices, and privacy tools. Fair and transparent dispute system with automated support for common issues. Many disputes can be settled between buyers and vendors without staff intervention.
🚀 Welcome to DrugHub Market 🌐
First, we designed and implemented an anonymous marketplace data collection and analysis pipeline to gather and identify opioids data in 16 anonymous marketplaces and forums over a period of almost 9 years between 2011 and 2020. Second, we fine-tuned the semantic comparison model proposed by Yuan et al [19] for opioid jargon detection, which can recognize the opioid jargon as innocent-looking terms and the dedicated terms only used in the anonymous marketplaces and forums. In this way, we generated a rich underground marketplace opioid vocabulary of 311 opioid keywords with 13 categories.
🚀 Welcome to DrugHub Market 🔥
Finally, we used natural language processing techniques to extract opioid trading information to characterize underground opioid commodities, suppliers, and transactions. Our research collected product listings and forum posts from 10 anonymous online market places and 6 forums. Our study determined the underground marketplace and forum list based on darknet site search engines and previous research works [20]. More specifically, we used darknet site search engines (such as Recon, Darknet live, Dark Eye, dark.fail, and DNStats [21,22]) to search underground marketplaces and forums and then manually validated their activeness.
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The breadth of the darknet’s product offering, combined with the relatively low barrier to entry, creates gateways to novel drug-using behaviours, where people try new substances just because they’ve suddenly been made available to them. Learn how we’re keeping our communities safer and improving access to mental health through the transition of nine supervised drug injection sites into HART Hubs. Become part of the #1 darknet marketplace trusted by over 500,000 users and 100k+ listings. Last month, a social services agency in Toronto launched a legal challenge against the law limiting supervise consumption sites, arguing it infringes on the Charter rights to life, liberty and security of person.
- This said… at this point in time I would not be surprised if DrugHub has been had it’s servers imaged by Law Enforcement and investigations at this point are probably underway.
- This is accomplished by setting up programs that connect patients and practitioners to the product.
- Drug Hub is a revolutionary XMR-only darknet marketplace built from the ground up with security, privacy, and user experience as top priorities.
- Drink Drug Hub is a website offering advice, guidance and accurate information about alcohol and other drugs.
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Figures 2 and 3 illustrate examples of opioid listings in The Versus Project and Alphabay. The opioid trader will also use an anonymous online forum (eg, The Hub Forum) to post promotional information to attract potential customers (step 3). Our study used opioid keywords and jargons to recognize listings and forum traces related to underground opioid trading activities. drug hub Our opioid jargon identification procedure implemented a modified semantic comparison model [19]. This model employed a neural network–based embedding technique to analyze the semantics of words in different corpora. In particular, in the semantic comparison model, the size of the input layer was doubled while not expanding either the hidden or the output layer.
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Among them is Amgen, which in April announced a $900 million expansion of its Ohio manufacturing facility as part of a $1.4 billion investment plan it said has created 750 jobs. In addition, J&J kicked off 2026 by announcing plans to build a next-generation cell therapy manufacturing site in Pennsylvania. Novartis broke ground on a 700,000-square-foot flagship manufacturing hub in December. Slated to open in by 2028, the project includes a new facility in Morrisville and a new site in Durham, as well as expansion of an existing Novartis facility in Durham. The company expects to create 700 new jobs in North Carolina by 2030. Pledged projects have landed in a handful of hotspots while giving rise to potential new hubs across the U.S.
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In particular, MALLET is retrained and evaluated via 10-fold cross-validation. We also applied the MALLET topic modeling toolkit (package cc.mallet.topics MALLET’s class in JavaDoc API) on the same data set to predict the type of topic. The baseline model was applied directly to the labeled data (Table 3) and evaluated using 10-fold cross-validation.
- The platform is built with robust security features, including anti-DDOS and anti-phishing measures, making it one of the most secure marketplaces on the Tor network.
- With Philadelphia a long-established pharma hotspot and Pittsburgh an emerging one, Pennsylvania’s life sciences sector employs 100,000 workers across nearly 3,100 companies that have secured more than 10,700 new life sciences patents over the past five years.
- Our goal here was to identify anonymous forum posts with the topics of opioid commodity promotion (eg, listing promotion) and review (eg, report fake opioid vendors).
- Each year, Frost & Sullivan presents this award to the company that has developed a product with innovative features and functionality that is gaining rapid acceptance in the market.
- The award recognizes the quality of the solution and the customer value enhancements it enables.
- Knowledge of these services helps one better understand the importance of hubs and the important role they play in specialty pharmacy.
How to Get Your Private Mirrors
We first conducted a whole-site crawl of anonymous online marketplaces and forums to solicit data. First, an opioid trader, who intends to list the selling information and find potential customers, will first access the anonymous online marketplaces and forums, using an anonymous browsing tool such as a Tor client or a web-to-Tor proxy (step 1 in Figure 1) [5,6]. Anonymous online marketplaces and forums usually operate as hidden Tor services, which can only be resolved through Tor (an anonymity network).
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The decision to operate clearnet mirrors alongside Tor-hidden services compounded the problem. While clearnet mirrors can provide redundancy and accessibility, they also expose the platform to the scrutiny of law enforcement agencies. In DrugHub’s case, the risks were amplified by its server’s geographical location and its choice of hosting providers.
Stream 1 – Mainstream HART Hubs
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- Figures 2 and 3 illustrate examples of opioid listings in The Versus Project and Alphabay.
In addition, we observed that 10 and 9 suppliers in Apollon and Empire, respectively, migrated from Agora 3 years after it shut down. Some of those suppliers’ IDs (ie, A1CRACK and DiazNL) are neither common words nor have special meaning. Those suppliers kept using the same IDs for years to gain reputation and familiarity from buyers. Overview of the opioid trading in the anonymous marketplaces and forums.
Ministry of Health
Hence, every word has 2 vectors, each describing the word’s relations with other words in one corpus. In the meantime, these 2 vectors are still comparable because they are used together in the neural network to train a single skip-gram model for predicting the surrounding windows of context words. We trained the semantic comparison model using the traces of Reddit as the benign corpora and the traces of the anonymous marketplaces/forums as the underground corpora. Thus, we identified 58 opioid jargon used in the anonymous marketplaces and forums (Table 2).
Drugs on the Menu: Greek Souvlaki Shop Exposed as Narcotics Hub
DrugHub Market is the #1 darknetmarketplace launched in August 2023 by the legendary team behind WhiteHouse Market. Now over 3 years strong, DrugHub boasts 100,000+ listings, over 500,000users, and more than 4,000 verifiedvendors. We are the premier platform for secure, private, Monero(XMR)-only transactions, with industry-leading security and uptime. It is becoming more common for medications to have strict storage and shipment requirements, especially for costly specialty medications.
We used the metrics of precision and recall to compare the performance of different topic modeling methods. As shown in Table 4, our results indicate that our approach significantly outperforms MALLET and the baseline model in terms of both precision and average recall. Data set summary of marketplaces and forums that were collected for this study. The geographic landscape of the Pancreatic And Bile Duct Cancer Drug Market reveals distinct growth trajectories across major regions, shaped by variations in industrial maturity, technology adoption, and investment intensity. North America continues to dominate the market, supported by a robust technological ecosystem, early adoption of advanced solutions, and sustained investments in innovation and automation.
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We partner with organizations of all sizes—from startups to Fortune 500 companies—to help them optimize strategies, strengthen competitiveness, and drive sustainable growth. Our commitment to quality research and client success has established us as a trusted name in global market intelligence. The Pancreatic And Bile Duct Cancer Drug Market refers to the global industry involved in the development, production, and deployment of Pancreatic And Bile Duct Cancer Drug solutions across various end-use sectors.
Topic Modeling of Forum Posts
This is the only official marketplace URL—any other address claiming to be Drug Hub is a phishing attempt. In Belleville, for example, where 13 people overdosed in roughly an hour in February, prompting a state of emergency, the mayor is expecting to receive the green light for a hub. Ontario NDP health critic France Gelinas was similarly supportive of the new funding and worried about the closure decision. Preparing amphetamine for injection changes it from a Class B to a Class A drug. Ecstasy pills are getting stronger and can contain powerful stimulants like PMA. Release explains different drug offences, and what happens if you get caught.
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We observed the same listings posted in different marketplaces and illustrate the dependency of the same opioid listings among different marketplaces. Note that we determined if 2 listings are identical by matching the same elements (ie, listing’s title and description information and the vendor’s name) in 2 listings. We observed that the marketplaces of Agora and Evolution shared 530 opioid listings from 290 unique supplier IDs.
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- Hub services work closely with companies who are able to automate this process and can expedite the prior authorization process from weeks to days.
- Considering social media data (eg, Twitter and Instagram), Nasralah et al [14] proposed a text mining framework to collect opioid data from social media and analyzed the most discussed topics to profile the opioid epidemic and crisis.
- Although a large body of current research is focused on pathways for treatment of opioid use disorder and analyzing deaths per treatment capacity of substance use providers, these research areas are limited to the demand side of the opioid epidemic [40,41].
- Lilly expects the project will bring 615 high-wage jobs for engineers, scientists, operations personnel and lab technicians, as well as 4,000 additional jobs during construction.
- The hub can complete benefits investigation, review formulary requirements, explore co-pay assistance offerings, and identify prior authorizations or step therapy requirements.
Nineteen new addiction treatment hubs will be operational in Ontario before 10 supervised consumption sites are forced to close their doors in March, the Ford government is promising. Hopefully, this has helped to illuminate some of the mystery behind hubs and show how they work to ease the specialty process for some patients. Hub services are most often created for medications that have a complicated path into the patient’s hands. Finally, hub services exist to provide patients, providers, and pharmacies with visibility to co-pay assistance programs. When a hub is operated by a pharmaceutical company, the hub can work with the pharmacy to provide patients with manufacturer co-pay assistance.
Mackey et al [13] collected tweets related to the opioid topic to identify illicit online pharmacies and study the illegal sale of opioids in online marketing. Cherian et al [12] gathered codeine misuse data from Instagram posts to understand how misuse is happening and its misused form. However, to the best of our knowledge, no large-scale study, which may cross multiple anonymous marketplaces and is cross-sectional, has been conducted to profile the opioid supply chain and unveil characteristics of opioid suppliers, commodities, and transactions.
Danny has worked in technology communications for more than 20 years, and has been writing about developments the longevity sector since 2019. With a keen interest in the transfer of technology to market, he focuses primarily on the companies working on cutting-edge solutions to aging and age-related diseases. He hung around with a rough crowd of Special Forces operatives in Fayetteville who drank heavily, took copious amounts of drugs and told graphic war stories in each others’ company while boasting about the numbers of people they had killed.
Because specialty medications are complex, third-party payers often require extensive paper work and clinical information for review before approving a drug. Hub services work closely with companies who are able to automate this process and can expedite the prior authorization process from weeks to days. The hub can complete benefits investigation, review formulary requirements, explore co-pay assistance offerings, and identify prior authorizations or step therapy requirements.
- Stay informed about the latest darknet marketplaces, secure browsing practices, and privacy tools.
- HUB meticulously crafts its targeted marketing campaigns to highlight specific applications of organoid technology to accelerate and improve drug testing.
- Everything’s bigger in Texas, the saying goes, and that’s true of Eli Lilly’s plans to build a new $6.5 billion manufacturing facility in Houston, marking one of the state’s biggest life sciences investments.
- Nontraditional methods, as presented here by studying the online supply chain, present a novel approach for governmental and other large-scale solutions.
- In addition, J&J kicked off 2026 by announcing plans to build a next-generation cell therapy manufacturing site in Pennsylvania.
- From a seemingly innocuous logo to systemic vulnerabilities, DrugHub’s downfall is a testament to the importance of vigilance in the digital age.
- M&A activities help companies expand capabilities, market reach, and competitive positioning.
Any pharmacist who works in the world of specialty pharmacy knows that the specialty process is simultaneously complex and expensive. Manufacturers are producing drugs for rare and serious conditions, often requiring limited distribution networks. Specialty drugs are well-known for their benefits (highly effective in the treatment of chronic diseases, have been known to greatly improve quality of life, and even save lives), as well as their challenges (hard to get and very expensive).
This analysis provides a comprehensive overview of the current market landscape, key regional trends, and the technological innovations shaping the future of pancreatic and bile duct cancer treatments across diverse geographic regions. To collect the listing information of 5 anonymous online marketplaces (ie, Apollon, Avaris, Darkbay, Empire, and The Versus Project), we conducted a whole-site crawl. The crawler was implemented in Python and used the Selenium module to launch browsers and to send crawling requests [24]. To avoid blocking from the marketplace, we provided as an input to the scraper a session cookie that we obtained by manually logging into the marketplace and solving a Completely Automated Public Turing test to tell Computers and Humans Apart (CAPTCHA). However, some sites, namely, the Empire Market, forced users to log out when the life span of the session cookie was expired. In addition, we set parameters such as sleeping time to limit the speed of crawling.
“Frost & Sullivan identifies HUB’s epithelial tissue-based technology as groundbreaking and innovative. This award recognizes HUB at the forefront of innovation and growth in the field of organoid technology, continuously improving its offerings to meet the dynamic needs of drug developers and providing state-of-the-arts solutions. As a pioneer in organoid technology, HUB offers transformative solutions to the pharmaceutical industry for more effective, faster, and ethical drug development. HUB develops disruptive PDOs that accurately replicate human drug responses compared to animal models and cell lines, greatly increasing the value and impact of drug development programs. Our team of seasoned analysts and researchers combines advanced methodologies, reliable data sources, and cutting-edge tools to produce detailed market reports, customized consulting solutions, and strategic recommendations.
